Scientists researching a case of lupus in a 7-year-old girl discovered a genetic mutation that led to her disease. This is important news, but what does it mean for people with other autoimmune diseases, or even other people with lupus?
The girl in this case had lupus at a very early age, which is not typical. The mutation in her genes is also unusual. But while this girl's genes might not be the cause of other lupus cases, the work gives scientists some insights into how autoimmune diseases emerge and it could help discover new treatments for lupus.
The work also suggests genetic links that connect different autoimmune diseases. We know, for instance, that those with one autoimmune disorder may likely develop another. Moreover, patients with various different autoimmune diseases often share common symptoms such as fatigue.
Researchers are looking for possible genetic connections. The Benaroya Research Institute (BRI) has mapped out common genes that connect 6 different autoimmune diseases, as shown above. By looking for therapies that affect any one of the genes, researchers can find treatments that work for all 6 autoimmune diseases shown.
The overlap among autoimmune diseases suggest they should not only be studied individually, but also collectively.
The Autoimmune Registry facilitates research by connecting patients to researchers. If you would like to join our efforts and provide information on your autoimmune condition, please join our registry or share it with a friend who has an autoimmune condition. Donations are also greatly appreciated.
